CL1: the first commercial biological computer powered by human neurons

Last update: March 7th 2025
  • The CL1 is the first commercial biological computer, developed by the Australian company Cortical Labs.
  • It uses human neurons grown in a laboratory that interact with a silicon chip to process information.
  • It operates with an operating system called biOS, which allows direct programming of neurons.
  • Its energy consumption is significantly lower compared to conventional chips, offering a more sustainable alternative.

CL1 biological computer

The advancement of computing has taken an unexpected turn with the arrival of CL1 , the world's first commercial biological computer. Developed by Cortical Labs , an Australian biotechnology company, this innovative device uses human neurons grown in the laboratory to perform calculations and store information, marking a turning point in the integration of biology and technology.

This computer not only aims to revolutionize artificial intelligence, but could also open new doors in medical and neuroscience research . Thanks to its energy efficiency and learning flexibility, the CL1 represents a promising alternative to traditional silicon processors.

How does CL1 work?

The core of this innovative system is a neural network created with human cells . These neurons are grown in a controlled environment and placed on a silicon chip equipped with electrodes, enabling communication between the biological tissue and the computer system . In this way, the CL1 is able to interpret data through electrical impulses and respond adaptively to different stimuli.

To coordinate this interaction, the computer uses an operating system called bioS (Biological Intelligence Operating System) . This platform simulates a virtual environment in which neurons react and adjust their behavior based on the information received. All of this results in more flexible and efficient learning, similar to that of a human brain. This form of learning resembles what is studied in the formal sciences , where reasoning structures and their applications are analyzed.

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A sustainable alternative in computing

One of the most remarkable aspects of the CL1 is its energy efficiency . While conventional AI chips demand large amounts of energy to train artificial intelligence models, this biological system consumes between 850 and 1,000 watts per unit, offering a significant reduction in electricity consumption.

CL1 Biological Chip

Furthermore, the CL1 does not require an external computer to operate , making it a more autonomous and environmentally friendly option compared to traditional GPU-based server configurations. This approach aligns perfectly with the search for new ways to revolutionize computing.

Potential applications of CL1

This biological computer has the potential to transform numerous disciplines , from artificial intelligence to neuroscience. Some of its applications include:

  • Medical Investigation: It allows the study of neuronal functioning without the need for animal testing, facilitating the development of new treatments for neurodegenerative diseases.
  • Machine learning: By harnessing the adaptive behavior of neurons, CL1 could improve AI algorithms and real-time decision-making.
  • Optimizing energy use: Its low consumption makes it viable for data centers looking to reduce their ecological impact.
  • Studies on biological intelligence: By mimicking brain systems, it can be used to study the evolution of thought and learning.

In fact, this type of computing can lead to the development of techniques similar to quantum algorithms , which are at the forefront of processing.

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Ethical and technological challenges

While this technology promises significant advances, it also raises ethical questions and technical challenges . The use of human cells in computing raises concerns about regulation and its impact on bioethics. Furthermore, the lifespan of neurons is limited, requiring their replacement every six months , which could pose a barrier to scalability.

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Neurons grown on a chip

To address these challenges, Cortical Labs has incorporated control measures into its CL1 and is working with international regulators to ensure the ethical and safe use of this emerging technology . This is a critical aspect that underscores the importance of understanding data processing in sensitive contexts, such as biological ones.

Availability and price

For those interested in acquiring the CL1, the first units will be commercially available in the second half of 2025. The initial price is estimated at $35,000 , positioning it as a tool primarily aimed at research and technological development centers.

In addition, Cortical Labs has adopted the “Wetware-as-a-Service” model , allowing researchers to access the computer remotely via the cloud without the need for additional hardware.

CL1 Research Center

The launch of CL1 marks an unprecedented advance in biological computing. By integrating human neurons into a computer system, this technology not only offers improvements in energy efficiency and learning capabilities, but also redefines the boundary between biology and artificial intelligence. With applications ranging from medical research to AI development, this biological computer could represent the beginning of a new era in computing.

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